Pub. Date : 2018 Nov
PMID : 30348300
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | analyzed a mouse model of erythropoietin-deficient anemia to show that during iron overload renal interstitial fibroblasts accumulate iron, and this impairs the hypoxia-driven transcription of the erythropoietin gene. | Iron | erythropoietin | Mus musculus |
| 2 | analyzed a mouse model of erythropoietin-deficient anemia to show that during iron overload renal interstitial fibroblasts accumulate iron, and this impairs the hypoxia-driven transcription of the erythropoietin gene. | Iron | erythropoietin | Mus musculus |
| 3 | analyzed a mouse model of erythropoietin-deficient anemia to show that during iron overload renal interstitial fibroblasts accumulate iron, and this impairs the hypoxia-driven transcription of the erythropoietin gene. | Iron | erythropoietin | Mus musculus |
| 4 | analyzed a mouse model of erythropoietin-deficient anemia to show that during iron overload renal interstitial fibroblasts accumulate iron, and this impairs the hypoxia-driven transcription of the erythropoietin gene. | Iron | erythropoietin | Mus musculus |
| 5 | The authors show that excess iron decreases levels of hypoxia-inducible transcription factor 2alpha (HIF2alpha), the main driver of erythropoietin production in hypoxia and anemia. | Iron | erythropoietin | Mus musculus |