Title : Modeling drug-drug interactions of AZD1208 with Vincristine and Daunorubicin on ligand-extrusion binding TMD-domains of multidrug resistance P-glycoprotein (ABCB1).

Pub. Date : 2019 Jan 1

PMID : 30339824






2 Functional Relationships(s)
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1 Modeling drug-drug interactions of AZD1208 with Vincristine and Daunorubicin on ligand-extrusion binding TMD-domains of multidrug resistance P-glycoprotein (ABCB1). Daunorubicin ATP binding cassette subfamily B member 1 Homo sapiens
2 In the present study, the molecular docking mechanism based on pharmacodynamic interactions between the ligands AZD1208 and recognized chemotherapy agents (Vincristine and Daunorubicin) with human ATP-binding cassette (ABC) transporters (ABCB1) was investigated. Daunorubicin ATP binding cassette subfamily B member 1 Homo sapiens