Title : Unravelling the suboptimal response of TP53-mutated chronic lymphocytic leukaemia to ibrutinib.

Pub. Date : 2019 Feb

PMID : 30338509






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Unravelling the suboptimal response of TP53-mutated chronic lymphocytic leukaemia to ibrutinib. ibrutinib tumor protein p53 Homo sapiens
2 TP53-disrupted chronic lymphocytic leukaemia (CLL) patients show a suboptimal long-term response to ibrutinib. ibrutinib tumor protein p53 Homo sapiens
3 We hereby report that ibrutinib-induced in vitro apoptosis and proliferation inhibition were significantly lower in TP53-mutated (TP53-M) CLL cells compared to TP53 wild-type cells. ibrutinib tumor protein p53 Homo sapiens
4 We hereby report that ibrutinib-induced in vitro apoptosis and proliferation inhibition were significantly lower in TP53-mutated (TP53-M) CLL cells compared to TP53 wild-type cells. ibrutinib tumor protein p53 Homo sapiens
5 We hereby report that ibrutinib-induced in vitro apoptosis and proliferation inhibition were significantly lower in TP53-mutated (TP53-M) CLL cells compared to TP53 wild-type cells. ibrutinib tumor protein p53 Homo sapiens