Pub. Date : 2018 Dec 14
PMID : 30337371
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Up-regulation of the kinase gene SGK1 by progesterone activates the AP-1-NDRG1 axis in both PR-positive and -negative breast cancer cells. | Progesterone | N-myc downstream regulated 1 | Homo sapiens |
| 2 | We further demonstrate a dual-phase transcriptional and post-transcriptional regulation of SGK1 in response to progesterone, leading to an up-regulation of NDRG1 that is mediated by a set of genes regulated by the transcription factor AP-1. | Progesterone | N-myc downstream regulated 1 | Homo sapiens |