Title : Dorsal ruffles enhance activation of Akt by growth factors.

Pub. Date : 2018 Nov 16

PMID : 30333140






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Microtubule depolymerization with nocodazole blocked CDR formation and inhibited phosphorylation of Akt in response to EGF but not PDGF. Nocodazole AKT serine/threonine kinase 1 Homo sapiens
2 Accordingly, stimulation with low concentrations of PDGF elicited lower levels of Akt phosphorylation, which, like responses to EGF, were inhibited by nocodazole. Nocodazole AKT serine/threonine kinase 1 Homo sapiens