Pub. Date : 2019 Apr
PMID : 30317657
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nicotine stimulates IL-6 expression by activating the AP-1 and STAT-3 pathways in human endothelial EA.hy926 cells. | Nicotine | JunB proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 2 | Nicotine stimulated IL-6 expression via the activator protein 1 (AP-1) transcription factor. | Nicotine | JunB proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 3 | Nicotine stimulated IL-6 expression via the activator protein 1 (AP-1) transcription factor. | Nicotine | JunB proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 4 | Our data demonstrate that nicotine induced IL-6 expression, which, in turn, enhanced the invasiveness of endothelial EA.hy926 cells, via activation of the p38 MAPK/AP-1 and ROS/STAT-3 signaling pathways. | Nicotine | JunB proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |