Title : Prevention of perinatal nicotine-induced bone marrow mesenchymal stem cell myofibroblast differentiation by augmenting the lipofibroblast phenotype.

Pub. Date : 2018 Nov 15

PMID : 30309879






1 Functional Relationships(s)
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1 Perinatal nicotine exposure resulted in decreased oil red O staining, triolein uptake, expression of PPARgamma, and its downstream target gene adipocyte differentiation-related protein by BMSCs, but enhanced alpha-smooth muscle actin and fibronectin expression, and activated Wnt signaling, all features indicative of their inhibited lipogenic, but enhanced myogenic potential. Nicotine fibronectin 1 Homo sapiens