Pub. Date : 2018 Oct 10
PMID : 30309036
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The methylation of DNA is regulated by DNA methyltransferases (DNMT1, DNMT3a, and DNMT3b) in the presence of S-adenosylmethionine (SAM), which serves as a methyl group donor. | S-Adenosylmethionine | DNA methyltransferase 1 | Homo sapiens |
| 2 | The methylation of DNA is regulated by DNA methyltransferases (DNMT1, DNMT3a, and DNMT3b) in the presence of S-adenosylmethionine (SAM), which serves as a methyl group donor. | S-Adenosylmethionine | DNA methyltransferase 1 | Homo sapiens |
| 3 | Increased availability of SAM enhances DNMT activity, while its metabolites, S-adenosyl-l-homocysteine (SAH) and decarboxylated S-adenosylmethionine (dcSAM), act to inhibit DNMT activity. | S-Adenosylmethionine | DNA methyltransferase 1 | Homo sapiens |