Pub. Date : 2018
PMID : 30308035
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Anti-metastatic effect of metformin via repression of interleukin 6-induced epithelial-mesenchymal transition in human colon cancer cells. | Metformin | interleukin 6 | Homo sapiens |
| 2 | Furthermore, pathway analysis revealed that the metformin-predicted group was characterized by decreased interleukin (IL)-6 pathway signaling, epithelial-mesenchymal transition, and colon cancer metastatic signaling. | Metformin | interleukin 6 | Homo sapiens |
| 3 | These findings suggest that blockade of IL-6-induced epithelial-mesenchymal transition is an antitumor mechanism of metformin. | Metformin | interleukin 6 | Homo sapiens |