Title : Mechanisms of beneficial effects of metformin on fatty acid-treated human islets

Pub. Date : 2018 Oct 1

PMID : 30307162






2 Functional Relationships(s)
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1 Mechanisms of beneficial effects of metformin on fatty acid-treated human islets Elevated levels of palmitate accentuate glucose-stimulated insulin secretion (GSIS) after short-term and cause beta-cell dysfunction after prolonged exposure. Palmitates insulin Homo sapiens
2 Inclusion of metformin during palmitate exposure normalized insulin secretion both after 2 and 7 days. Palmitates insulin Homo sapiens