Title : Hypoxic stabilization of mRNA is HIF-independent but requires mtROS.

Pub. Date : 2018

PMID : 30305827






1 Functional Relationships(s)
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1 Interestingly, treatment of HEK293T cells with the mitochondrial inhibitors rotenone and myxothiazol, or the glutathione peroxidase mimetic ebselen did prevent the hypoxic stabilization of VEGF, MYC, and CYR61, suggesting a role for mtROS in the process. myxothiazol vascular endothelial growth factor A Homo sapiens