Title : Cytoplasmic p21 Mediates 5-Fluorouracil Resistance by Inhibiting Pro-Apoptotic Chk2.

Pub. Date : 2018 Oct 9

PMID : 30304835






3 Functional Relationships(s)
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1 Cytoplasmic p21 Mediates 5-Fluorouracil Resistance by Inhibiting Pro-Apoptotic Chk2. Fluorouracil H3 histone pseudogene 16 Homo sapiens
2 Here, we show for the first time that cytoplasmic p21 mediates 5-Fluorouracil (5FU) resistance by shuttling p-Chk2 out of the nucleus to protect the tumor cells from its pro-apoptotic functions. Fluorouracil H3 histone pseudogene 16 Homo sapiens
3 Here, we show for the first time that cytoplasmic p21 mediates 5-Fluorouracil (5FU) resistance by shuttling p-Chk2 out of the nucleus to protect the tumor cells from its pro-apoptotic functions. Fluorouracil H3 histone pseudogene 16 Homo sapiens