Title : Chrysophanol selectively represses breast cancer cell growth by inducing reactive oxygen species production and endoplasmic reticulum stress via AKT and mitogen-activated protein kinase signal pathways.

Pub. Date : 2018 Dec 1

PMID : 30300626






2 Functional Relationships(s)
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Protein Name
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1 Reactive oxygen species (ROS) overproduction by chrysophanol resulted in endoplasmic reticulum (ER) stress, leading to an increase in PERK, eIF2alpha, GADD153, and IRE1alpha levels in BT-474 and MCF-7 cells. Reactive Oxygen Species DNA damage inducible transcript 3 Homo sapiens
2 Reactive oxygen species (ROS) overproduction by chrysophanol resulted in endoplasmic reticulum (ER) stress, leading to an increase in PERK, eIF2alpha, GADD153, and IRE1alpha levels in BT-474 and MCF-7 cells. Reactive Oxygen Species DNA damage inducible transcript 3 Homo sapiens