Title : A 5‑lipoxygenase-specific sequence motif impedes enzyme activity and confers dependence on a partner protein.

Pub. Date : 2019 Apr

PMID : 30291962






1 Functional Relationships(s)
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1 These data suggest that the KKK motif limits 5-LOX activity and that this attenuated activity must be compensated by the presence of FLAP as a partner protein for effective LT biosynthesis. Leukotrienes arachidonate 5-lipoxygenase activating protein Homo sapiens