Title : Autonomic interplay in VIP-induced tracheal smooth muscle relaxation.

Pub. Date : 1986 Dec

PMID : 3029132






5 Functional Relationships(s)
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1 VIP-induced inhibitory responses of the guinea-pig tracheal pouch, an in vivo preparation designed to demonstrate non-noradrenergic non-cholinergic innervation, where determined in chloraloseurethane anaesthetized animals under control conditions, or pretreated with atropine, propranolol, both atropine and propranolol or atropine-propranolol with indomethacin. Propranolol VIP peptides Cavia porcellus
2 VIP-induced inhibitory responses of the guinea-pig tracheal pouch, an in vivo preparation designed to demonstrate non-noradrenergic non-cholinergic innervation, where determined in chloraloseurethane anaesthetized animals under control conditions, or pretreated with atropine, propranolol, both atropine and propranolol or atropine-propranolol with indomethacin. Propranolol VIP peptides Cavia porcellus
3 The group that received atropine alone and the combination of atropine and propranolol showed the least relaxation to VIP. Propranolol VIP peptides Cavia porcellus
4 The significantly greater relaxation of the pouch to VIP in the propranolol treated group suggested that the non-noradrenergic inhibitory mechanism for VIP is dependent upon the existing smooth muscle tone of the pouch. Propranolol VIP peptides Cavia porcellus
5 The significantly greater relaxation of the pouch to VIP in the propranolol treated group suggested that the non-noradrenergic inhibitory mechanism for VIP is dependent upon the existing smooth muscle tone of the pouch. Propranolol VIP peptides Cavia porcellus