Title : The 11-Kilodalton Nonstructural Protein of Human Parvovirus B19 Facilitates Viral DNA Replication by Interacting with Grb2 through Its Proline-Rich Motifs.

Pub. Date : 2019 Jan 1

PMID : 30282717






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In consistence, in vivo during infection, one proline-rich motif was enough for 11-kDa to significantly reduce phosphorylation of extracellular signal-regulated kinase (ERK). Proline mitogen-activated protein kinase 1 Homo sapiens
2 In consistence, in vivo during infection, one proline-rich motif was enough for 11-kDa to significantly reduce phosphorylation of extracellular signal-regulated kinase (ERK). Proline mitogen-activated protein kinase 1 Homo sapiens
3 Mutations of all three proline-rich motifs of 11-kDa abolished its capability to reduce ERK activity and, accordingly, decreased viral DNA replication. Proline mitogen-activated protein kinase 1 Homo sapiens