Title : Huntingtin suppression restores cognitive function in a mouse model of Huntington's disease.

Pub. Date : 2018 Oct 3

PMID : 30282695






1 Functional Relationships(s)
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1 We previously identified HTT single-nucleotide polymorphisms (SNPs) tightly linked to the HD mutation and developed antisense oligonucleotides (ASOs) targeting HD-SNPs that selectively suppress mutant HTT. Oligonucleotides huntingtin Mus musculus