Pub. Date : 2019 Mar
PMID : 30272820
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The cholesterol hydroxylase/lyase (CHL) system, consisting of cytochrome P450scc, adrenodoxin (Adx) and adrenodoxin reductase (AdR), initiates mammalian steroidogenesis, converting cholesterol to pregnenolone. | Pregnenolone | cytochrome P450 family 11 subfamily A member 1 | Homo sapiens |
| 2 | Despite the spatial separation of expressed P450scc and redox partners, the transfected HEK293T cells were able to convert the steroid substrates of cytochrome P450scc to pregnenolone, whereas control HEK293T cells were not catalytically active. | Pregnenolone | cytochrome P450 family 11 subfamily A member 1 | Homo sapiens |