Title : Aliskiren reduces the release of soluble (pro)renin receptor from human umbilical vein endothelial cells.

Pub. Date : 2018 Sep

PMID : 30271601






2 Functional Relationships(s)
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1 The present study examined the effect of aliskiren, the first orally active direct renin inhibitor, on the protein levels of (P)RR using cultured human umbilical vein endothelial cells (HUVECs). aliskiren renin Homo sapiens
2 Furthermore, aliskiren treatment decreased not only the level of exogenous prorenin that bound to the membranes of HUVECs, but also the renin activity derived from this binding activity. aliskiren renin Homo sapiens