Pub. Date : 2018
PMID : 30257253
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | miR-128 Targets the SIRT1/ROS/DR5 Pathway to Sensitize Colorectal Cancer to TRAIL-Induced Apoptosis. | mir-128 | sirtuin 1 | Homo sapiens |
| 2 | Mechanistically, bioinformatics, western blot analysis, and luciferase reporter assays showed that miR-128 directly targeted sirtuin 1 (SIRT1) in CRC cells. | mir-128 | sirtuin 1 | Homo sapiens |
| 3 | Mechanistically, bioinformatics, western blot analysis, and luciferase reporter assays showed that miR-128 directly targeted sirtuin 1 (SIRT1) in CRC cells. | mir-128 | sirtuin 1 | Homo sapiens |
| 4 | miR-128 overexpression suppressed SIRT1 expression, which promoted the production of ROS in TRAIL-treated CRC cells. | mir-128 | sirtuin 1 | Homo sapiens |