Title : Melatonin Ameliorates the Progression of Atherosclerosis via Mitophagy Activation and NLRP3 Inflammasome Inhibition.

Pub. Date : 2018

PMID : 30254716






1 Functional Relationships(s)
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1 Both Sirt3-siRNA and autophagy inhibitor 3-MA partially abolished the beneficial effects of melatonin on mitoROS clearance and NLRP3 inflammasome activation, indicating the crucial role of Sirt3-mediated mitophagy. 3-methyladenine NLR family, pyrin domain containing 3 Mus musculus