Title : Exploiting MCL1 Dependency with Combination MEK + MCL1 Inhibitors Leads to Induction of Apoptosis and Tumor Regression in KRAS-Mutant Non-Small Cell Lung Cancer.

Pub. Date : 2018 Dec

PMID : 30254092






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Susceptibility to BH3 mimetics that target either MCL1 or BCL-xL was determined by the differential binding of proapoptotic BCL2 proteins to MCL1 or BCL-xL, respectively. BH 3 BCL2 like 1 Homo sapiens
2 Susceptibility to BH3 mimetics that target either MCL1 or BCL-xL was determined by the differential binding of proapoptotic BCL2 proteins to MCL1 or BCL-xL, respectively. BH 3 BCL2 like 1 Homo sapiens