Title : TRPV1 mediates capsaicin-stimulated metabolic activity but not cell death or inhibition of interleukin-1β release in human THP-1 monocytes.

Pub. Date : 2018 Dec 1

PMID : 30244119






2 Functional Relationships(s)
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1 Finally, capsaicin (<=125 muM) significantly increased lipopolysaccharide-stimulated IL-6 and TNF-alpha release from THP-1 cells, whereas phytohaemagglutinin-stimulated IL-1beta, TNF-alpha, MCP-1 and IL-6 release were concentration-dependently inhibited by capsaicin. Capsaicin tumor necrosis factor Homo sapiens
2 Finally, capsaicin (<=125 muM) significantly increased lipopolysaccharide-stimulated IL-6 and TNF-alpha release from THP-1 cells, whereas phytohaemagglutinin-stimulated IL-1beta, TNF-alpha, MCP-1 and IL-6 release were concentration-dependently inhibited by capsaicin. Capsaicin tumor necrosis factor Homo sapiens