Title : Characterization of Precursor-Dependent Steroidogenesis in Human Prostate Cancer Models.

Pub. Date : 2018 Sep 20

PMID : 30241348






1 Functional Relationships(s)
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1 Pregnenolone, progesterone, 17-OH-pregnenolone, and 17-OH-progesterone increased C21 steroid (5-pregnan-3,20-dione, 5-pregnan-3,17-diol-20-one, 5-pregnan-3-ol-20-one) formation in the backdoor pathway, and demonstrated a trend of stimulating dihydroepiandrosterone or its precursors in the backdoor pathway in LNCaP and 22Rv1 cells. Pregnenolone TBL1X/Y related 1 Homo sapiens