Title : Growth hormone responses to clonidine and GRF in spontaneously hypertensive rats: neuroendocrine evidence for an enhanced responsiveness of brain alpha 2-adrenoceptors in genetical hypertension.

Pub. Date : 1986 Dec 1

PMID : 3023778






5 Functional Relationships(s)
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1 Growth hormone responses to clonidine and GRF in spontaneously hypertensive rats: neuroendocrine evidence for an enhanced responsiveness of brain alpha 2-adrenoceptors in genetical hypertension. Clonidine gonadotropin releasing hormone receptor Rattus norvegicus
2 Clonidine induces growth hormone (GH) release in rat. Clonidine gonadotropin releasing hormone receptor Rattus norvegicus
3 Clonidine induces growth hormone (GH) release in rat. Clonidine gonadotropin releasing hormone receptor Rattus norvegicus
4 In the present study it is demonstrated that spontaneously hypertensive rats (SHR) of the Wistar-Kyoto strain display enhanced GH responses to clonidine as compared to normotensive Wistar-Kyoto control rats. Clonidine gonadotropin releasing hormone receptor Rattus norvegicus
5 Since the enhanced GH responses to clonidine were observed also in young, prehypertensive SHR they are probably not secondary to the elevated blood pressure. Clonidine gonadotropin releasing hormone receptor Rattus norvegicus