Title : Pathological Interactions Between Mutant Thyroid Hormone Receptors and Corepressors and Their Modulation by a Thyroid Hormone Analogue with Therapeutic Potential.

Pub. Date : 2018 Dec

PMID : 30235988






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 A strong impairment of T3-binding for TRbeta mutants was shown compared to TRIAC and NH-3 and could explain the different efficiencies of the different ligands in releasing corepressors from the studied TRbeta mutants. Triiodothyronine T cell receptor alpha locus Homo sapiens
2 A strong impairment of T3-binding for TRbeta mutants was shown compared to TRIAC and NH-3 and could explain the different efficiencies of the different ligands in releasing corepressors from the studied TRbeta mutants. Triiodothyronine T cell receptor alpha locus Homo sapiens