Title : UBE2G1 governs the destruction of cereblon neomorphic substrates.

Pub. Date : 2018 Sep 20

PMID : 30234487






1 Functional Relationships(s)
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1 For example, UBE2G1 inactivation significantly attenuated the degradation of myeloma survival factors IKZF1 and IKZF3 induced by lenalidomide and pomalidomide, hence conferring drug resistance. Lenalidomide IKAROS family zinc finger 1 Homo sapiens