Pub. Date : 2018 Sep 20
PMID : 30232325
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Finally, we report that pharmacological inhibition of the Abeta-Dkk1-Abeta positive feedback loop with the drug fasudil can restore the balance between Wnt pathways, prevent dendritic spine withdrawal in vitro, and reduce Abeta load in vivo in mice with advanced amyloid pathology. | fasudil | amyloid beta (A4) precursor protein | Mus musculus |
| 2 | Finally, we report that pharmacological inhibition of the Abeta-Dkk1-Abeta positive feedback loop with the drug fasudil can restore the balance between Wnt pathways, prevent dendritic spine withdrawal in vitro, and reduce Abeta load in vivo in mice with advanced amyloid pathology. | fasudil | amyloid beta (A4) precursor protein | Mus musculus |
| 3 | Finally, we report that pharmacological inhibition of the Abeta-Dkk1-Abeta positive feedback loop with the drug fasudil can restore the balance between Wnt pathways, prevent dendritic spine withdrawal in vitro, and reduce Abeta load in vivo in mice with advanced amyloid pathology. | fasudil | amyloid beta (A4) precursor protein | Mus musculus |