Pub. Date : 2018
PMID : 30228819
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | As this reactive metabolite is detoxified mainly by enzymatic reactions, involving microsomal epoxide hydrolase and/or GSH-S-transferases and these enzymes are polymorphically expressed in humans, arene oxide toxicity is increased when epoxide hydrolase or GSH-S-transferases is either defective or inhibited or a depletion of intracellular glutathione levels is taking place. | Benzene oxide | glutathione synthetase | Homo sapiens |
| 2 | As this reactive metabolite is detoxified mainly by enzymatic reactions, involving microsomal epoxide hydrolase and/or GSH-S-transferases and these enzymes are polymorphically expressed in humans, arene oxide toxicity is increased when epoxide hydrolase or GSH-S-transferases is either defective or inhibited or a depletion of intracellular glutathione levels is taking place. | Benzene oxide | glutathione synthetase | Homo sapiens |