Title : The PPARĪ“ agonist GW0742 restores neuroimmune function by regulating Tim-3 and Th17/Treg-related signaling in the BTBR autistic mouse model.

Pub. Date : 2018 Nov

PMID : 30227151






2 Functional Relationships(s)
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1 The PPARdelta agonist GW0742 restores neuroimmune function by regulating Tim-3 and Th17/Treg-related signaling in the BTBR autistic mouse model. GW0742 hepatitis A virus cellular receptor 2 Mus musculus
2 GW0742 attenuated the expression of inflammatory markers such as IL-17A, RORgammaT, Stat3, TIM-3, and IFN-gamma, while upregulating anti-inflammatory markers such as IL-10/Foxp3 both in the brain and periphery of BTBR mice. GW0742 hepatitis A virus cellular receptor 2 Mus musculus