Title : Converting enzyme inhibition: search for additional mechanisms of action.

Pub. Date : 1986

PMID : 3022509






1 Functional Relationships(s)
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1 Additional mechanisms of action postulated to explain the effect of ACE-inhibitors include inhibition of angiotensin II formation in the central RAS, neutralization of renin activity in the vascular wall, blockade of vasoconstrictor response to sympathetic nerve stimulation, and possible involvement of prostaglandins linked, for instance, to bradykinin accumulation. Prostaglandins angiotensin I converting enzyme Homo sapiens