Pub. Date : 2018 Sep 17
PMID : 30224639
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Therefore, we wanted to explore the molecular interplay between autophagy, anoikis, and ROS in relation to LC3B. | Reactive Oxygen Species | microtubule associated protein 1 light chain 3 beta | Homo sapiens |
| 2 | We observed enhanced LC3B level along with increased expression of p62 and modulation of other autophagy-related molecules (Atg 3, 5, 7, 12, 16L1 and Beclin1) by inducing oxidative-stress in ovarian cancer cells using a ROS-producing pro-oxidant molecule. | Reactive Oxygen Species | microtubule associated protein 1 light chain 3 beta | Homo sapiens |
| 3 | Moreover, such upregulation of LC3B via ROS enhanced several apoptotic molecules. | Reactive Oxygen Species | microtubule associated protein 1 light chain 3 beta | Homo sapiens |
| 4 | Furthermore, LC3B-dependent apoptosis was decreased by inhibiting ROS, indicating a possible link between ROS, LC3B, and apoptosis. | Reactive Oxygen Species | microtubule associated protein 1 light chain 3 beta | Homo sapiens |
| 5 | Furthermore, LC3B-dependent apoptosis was decreased by inhibiting ROS, indicating a possible link between ROS, LC3B, and apoptosis. | Reactive Oxygen Species | microtubule associated protein 1 light chain 3 beta | Homo sapiens |
| 6 | Furthermore, LC3B-dependent apoptosis was decreased by inhibiting ROS, indicating a possible link between ROS, LC3B, and apoptosis. | Reactive Oxygen Species | microtubule associated protein 1 light chain 3 beta | Homo sapiens |
| 7 | Additionally, ROS-induced enhanced LC3B promoted detachment-induced cell death (anoikis). | Reactive Oxygen Species | microtubule associated protein 1 light chain 3 beta | Homo sapiens |