Pub. Date : 2018 Dec 1
PMID : 30224519
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Human DnaJB6 Antiamyloid Chaperone Protects Yeast from Polyglutamine Toxicity Separately from Spatial Segregation of Aggregates. | polyglutamine | DnaJ heat shock protein family (Hsp40) member B6 | Homo sapiens |
| 2 | Polyglutamine (polyQ) aggregates are associated with pathology in protein-folding diseases and with toxicity in the yeast Saccharomyces cerevisiae Protection from polyQ toxicity in yeast by human DnaJB6 coincides with sequestration of aggregates. | polyglutamine | DnaJ heat shock protein family (Hsp40) member B6 | Homo sapiens |
| 3 | Polyglutamine (polyQ) aggregates are associated with pathology in protein-folding diseases and with toxicity in the yeast Saccharomyces cerevisiae Protection from polyQ toxicity in yeast by human DnaJB6 coincides with sequestration of aggregates. | polyglutamine | DnaJ heat shock protein family (Hsp40) member B6 | Homo sapiens |
| 4 | Polyglutamine (polyQ) aggregates are associated with pathology in protein-folding diseases and with toxicity in the yeast Saccharomyces cerevisiae Protection from polyQ toxicity in yeast by human DnaJB6 coincides with sequestration of aggregates. | polyglutamine | DnaJ heat shock protein family (Hsp40) member B6 | Homo sapiens |
| 5 | Our findings suggest DnaJB6 binds to smaller polyQ aggregates to block their toxicity. | polyglutamine | DnaJ heat shock protein family (Hsp40) member B6 | Homo sapiens |