Pub. Date : 2018 Sep 14
PMID : 30223436
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Structural Features of Amyloid Fibrils Formed from the Full-Length and Truncated Forms of Beta-2-Microglobulin Probed by Fluorescent Dye Thioflavin T. | thioflavin T | beta-2-microglobulin | Homo sapiens |
| 2 | Spectroscopic analysis of the obtained samples allowed us to detect one binding mode (type) of ThT interaction with all the studied variants of beta2M amyloid fibrils with affinity ~104 M-1. | thioflavin T | beta-2-microglobulin | Homo sapiens |
| 3 | The observed differences in the ThT-beta2M fibrils binding parameters and characteristics of the bound dye allowed to prove not only the difference of the DeltaN10beta2m fibrils from other beta2M fibrils (that can be detected visually, for example, by transmission electron microscopy (TEM), but also the differences between beta2m and DeltaN6beta2m fibrils (that can not be unequivocally confirmed by other approaches). | thioflavin T | beta-2-microglobulin | Homo sapiens |
| 4 | The observed differences in the ThT-beta2M fibrils binding parameters and characteristics of the bound dye allowed to prove not only the difference of the DeltaN10beta2m fibrils from other beta2M fibrils (that can be detected visually, for example, by transmission electron microscopy (TEM), but also the differences between beta2m and DeltaN6beta2m fibrils (that can not be unequivocally confirmed by other approaches). | thioflavin T | beta-2-microglobulin | Homo sapiens |
| 5 | The observed differences in the ThT-beta2M fibrils binding parameters and characteristics of the bound dye allowed to prove not only the difference of the DeltaN10beta2m fibrils from other beta2M fibrils (that can be detected visually, for example, by transmission electron microscopy (TEM), but also the differences between beta2m and DeltaN6beta2m fibrils (that can not be unequivocally confirmed by other approaches). | thioflavin T | beta-2-microglobulin | Homo sapiens |