Pub. Date : 2018
PMID : 30221067
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To this aim, we used the pro-ICD agents mitoxantrone and doxorubicin and found that both agents could induce cell death and stimulate the release/exposure of the strictly required DAMPs in melanoma cells: i) calreticulin (CRT) exposure on the cell membrane; ii) ATP secretion; iii) type I IFNs gene up-regulation and iv) HMGB1 secretion, highlighting no interference by oncogenic BRAF. | Doxorubicin | calreticulin | Homo sapiens |