Title : Tumor-associated carbonic anhydrase isoform IX and XII inhibitory properties of certain isatin-bearing sulfonamides endowed with in vitro antitumor activity towards colon cancer.

Pub. Date : 2018 Dec

PMID : 30219719






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 All the investigated sulfonamides displayed single- or double-digit nanomolar inhibitory activities towards both hCA IX (KIs: 6.2-64.8 nM) and XII (KIs: 7.1-55.6 nM) isoforms. Sulfonamides carbonic anhydrase 9 Homo sapiens