Title : The Beta-Hydroxybutyrate Suppresses the Migration of Glioma Cells by Inhibition of NLRP3 Inflammasome.

Pub. Date : 2018 Nov

PMID : 30218403






3 Functional Relationships(s)
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1 Our results indicated that administration of BHB suppressed C6 cells migration and NLRP3 inflammasome activation, reducing the levels of activated cysteinyl aspartate-specific proteinase 1 (caspase-1) and mature Interleukin 1beta (IL-1beta). 3-Hydroxybutyric Acid interleukin 1 beta Homo sapiens
2 Our results indicated that administration of BHB suppressed C6 cells migration and NLRP3 inflammasome activation, reducing the levels of activated cysteinyl aspartate-specific proteinase 1 (caspase-1) and mature Interleukin 1beta (IL-1beta). 3-Hydroxybutyric Acid interleukin 1 beta Homo sapiens
3 BHB also counteracted the LPS/ATP-promoted cell migration by suppressing the activation of caspase-1 and the maturation of IL-1beta. 3-Hydroxybutyric Acid interleukin 1 beta Homo sapiens