Pub. Date : 2018 Nov
PMID : 30218403
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Beta-hydroxybutyrate (BHB) is a ketone body that has recently been reported to exert anti-inflammatory effects via inhibition of NOD-like receptor pyrin domain-containing 3 (NLRP3) inflammasome. | 3-Hydroxybutyric Acid | NLR family pyrin domain containing 3 | Homo sapiens |
| 2 | Beta-hydroxybutyrate (BHB) is a ketone body that has recently been reported to exert anti-inflammatory effects via inhibition of NOD-like receptor pyrin domain-containing 3 (NLRP3) inflammasome. | 3-Hydroxybutyric Acid | NLR family pyrin domain containing 3 | Homo sapiens |
| 3 | Beta-hydroxybutyrate (BHB) is a ketone body that has recently been reported to exert anti-inflammatory effects via inhibition of NOD-like receptor pyrin domain-containing 3 (NLRP3) inflammasome. | 3-Hydroxybutyric Acid | NLR family pyrin domain containing 3 | Homo sapiens |
| 4 | Beta-hydroxybutyrate (BHB) is a ketone body that has recently been reported to exert anti-inflammatory effects via inhibition of NOD-like receptor pyrin domain-containing 3 (NLRP3) inflammasome. | 3-Hydroxybutyric Acid | NLR family pyrin domain containing 3 | Homo sapiens |
| 5 | Our results indicated that administration of BHB suppressed C6 cells migration and NLRP3 inflammasome activation, reducing the levels of activated cysteinyl aspartate-specific proteinase 1 (caspase-1) and mature Interleukin 1beta (IL-1beta). | 3-Hydroxybutyric Acid | NLR family pyrin domain containing 3 | Homo sapiens |
| 6 | Our results suggested that BHB inhibits the activation of NLRP3 inflammasome in C6 glioma cells and consequently suppressed the C6 cell migration. | 3-Hydroxybutyric Acid | NLR family pyrin domain containing 3 | Homo sapiens |
| 7 | These findings also implicated that by inhibiting NLRP3 inflammasome, BHB reduced the inflammatory microenvironment which provided ancillary therapeutic benefits for the intervention of glioma. | 3-Hydroxybutyric Acid | NLR family pyrin domain containing 3 | Homo sapiens |