Title : Induction of prostacyclin biosynthesis is closely associated with increased guanosine 3',5'-cyclic monophosphate accumulation in cultured human endothelium.

Pub. Date : 1986 Nov

PMID : 3021818






1 Functional Relationships(s)
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1 Stimuli of prostacyclin (PGI2) biosynthesis such as thrombin, bradykinin, histamine, and A23187 increase guanosine 3",5"-cyclic monophosphate (cyclic GMP) levels in primary monolayer cultures of human umbilical vein endothelium by about twofold. Cyclic GMP kininogen 1 Homo sapiens