Pub. Date : 2018 Oct 5
PMID : 30216848
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Furthermore, in vitro COX-1/COX-2 inhibition testing showed that the compounds 4b, 6c, 10b, and 10c exhibited effective COX-2 inhibition, with IC50 values of 0.40-1.20 muM, and selectivity index (SI) values of >62.50-20.83, using celecoxib as a reference drug (IC50 = 0.11 muM; COX-2 SI: >227.20). | Celecoxib | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 2 | Furthermore, in vitro COX-1/COX-2 inhibition testing showed that the compounds 4b, 6c, 10b, and 10c exhibited effective COX-2 inhibition, with IC50 values of 0.40-1.20 muM, and selectivity index (SI) values of >62.50-20.83, using celecoxib as a reference drug (IC50 = 0.11 muM; COX-2 SI: >227.20). | Celecoxib | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |