Title : Effect of cellular fatty acid composition on the phospholipase A2 activity of bone marrow-derived macrophages, and their ability to induce lucigenin-dependent chemiluminescence.

Pub. Date : 1986 Oct 31

PMID : 3021238






2 Functional Relationships(s)
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1 The fatty acid composition of the cellular membranes directly modulates functional abilities of the macrophages such as the generation of superoxide anion and phospholipase A2 activity in response to phorbol ester and zymosan. Zymosan phospholipase A2, group IB, pancreas Mus musculus
2 Incorporation of unsaturated fatty acids into macrophage phospholipids leads to an increase of O2- production as measured by lucigenin-dependent chemiluminescence and to an increased phospholipase A2 activity after challenge with phorbol ester or zymosan. Zymosan phospholipase A2, group IB, pancreas Mus musculus