Title : mTORC2 modulates the amplitude and duration of GFAT1 Ser-243 phosphorylation to maintain flux through the hexosamine pathway during starvation.

Pub. Date : 2018 Oct 19

PMID : 30201609






3 Functional Relationships(s)
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1 mTORC2 modulates the amplitude and duration of GFAT1 Ser-243 phosphorylation to maintain flux through the hexosamine pathway during starvation. Hexosamines glutamine--fructose-6-phosphate transaminase 1 Homo sapiens
2 Recently, we have shown that mTOR complex 2 (mTORC2) modulates the hexosamine biosynthetic pathway (HBP) by promoting the expression of the key enzyme of the HBP, glutamine:fructose-6-phosphate aminotransferase 1 (GFAT1). Hexosamines glutamine--fructose-6-phosphate transaminase 1 Homo sapiens
3 Recently, we have shown that mTOR complex 2 (mTORC2) modulates the hexosamine biosynthetic pathway (HBP) by promoting the expression of the key enzyme of the HBP, glutamine:fructose-6-phosphate aminotransferase 1 (GFAT1). Hexosamines glutamine--fructose-6-phosphate transaminase 1 Homo sapiens