Title : Selective Inhibition on Organic Cation Transporters by Carvedilol Protects Mice from Cisplatin-Induced Nephrotoxicity.

Pub. Date : 2018 Sep 6

PMID : 30191328






1 Functional Relationships(s)
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1 METHODS: The inhibition by select compounds on the uptake of the probe substrate metformin was assessed in HEK293 cells overexpressing human OCT2, OCT1, MATE1, MATE2-K, and mouse Oct2, Oct1, and Mate1. Metformin solute carrier family 22 member 1 Homo sapiens