Title : Nanoscale remodeling of ryanodine receptor cluster size underlies cerebral microvascular dysfunction in Duchenne muscular dystrophy.

Pub. Date : 2018 Oct 9

PMID : 30181262






1 Functional Relationships(s)
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1 Inhibition of RyRs with tetracaine and blocking of BK channels with paxilline restored myogenic tone to control levels, demonstrating that enhanced RyR and BK channel activity is responsible for the diminished pressure-induced constriction of arteries and arterioles from mdx mice. Tetracaine ryanodine receptor 1, skeletal muscle Mus musculus