Title : MicroRNA-19b alleviates lipopolysaccharide-induced inflammatory injury in human intestinal cells by up-regulation of Runx3.

Pub. Date : 2018 Aug

PMID : 30178853






2 Functional Relationships(s)
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1 Overexpression of Runx3 reversed the miR-19b knockdown-induced Caco2 cell viability inhibition, apoptosis enhancement, inflammatory factors expressions and NF-kappaB and PI3K/AKT signaling pathways activation. caco2 RUNX family transcription factor 3 Homo sapiens
2 CONCLUSIONS: Our study demonstrated that miR-19b alleviated LPS-induced Caco2 cell inflammatory injury via up-regulation of Runx3 and deactivation of NF-kappaB and PI3K/AKT signaling pathways. caco2 RUNX family transcription factor 3 Homo sapiens