Pub. Date : 2018 Aug
PMID : 30169917
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We identified lipids in plasma from 44 healthy subjects that correlated with CES1 activity as determined by PK parameters of methylphenidate including a ceramide (q value = 0.001) and a phosphatidylcholine (q value = 0.005). | Phosphatidylcholines | carboxylesterase 1 | Homo sapiens |
| 2 | Carriers of the CES1 143E allele had decreased methylphenidate metabolism and altered concentration of this phosphatidylcholine (q value = 0.040) and several high polyunsaturated fatty acid lipids (PUFAs). | Phosphatidylcholines | carboxylesterase 1 | Homo sapiens |