Title : Regulation of the NLRP3 inflammasome and macrophage pyroptosis by the p38 MAPK signaling pathway in a mouse model of acute lung injury.

Pub. Date : 2018 Nov

PMID : 30152849






1 Functional Relationships(s)
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1 However, blocking p38 MAPK signaling through the inhibitor SB203580 significantly suppressed the acute lung injury and excessive lung inflammation in vivo, consistent with the reduced expression of the NLRP3 inflammasome and IL-1beta and cleavage of caspase-1. SB 203580 interleukin 1 beta Mus musculus