Title : O-GlcNAc modification of eIF4GI acts as a translational switch in heat shock response.

Pub. Date : 2018 Oct

PMID : 30127386






1 Functional Relationships(s)
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1 Mechanistically, we show that stress-induced eIF4GI O-GlcNAcylation repels poly(A)-binding protein 1 and promotes SG disassembly, thereby licensing stress mRNAs for selective translation. poly( eukaryotic translation initiation factor 4 gamma 1 Homo sapiens