Title : Synthetic isoflavones and doping: A novel class of aromatase inhibitors?

Pub. Date : 2019 Feb

PMID : 30118172






1 Functional Relationships(s)
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1 We have evaluated in vitro the effects of two synthetic isoflavones, methoxyisoflavone and ipriflavone, on the catalytic activity of human aromatase (CYP19), the enzyme catalyzing the conversion of androgens (ie, testosterone or androstenedione) to estrogens (ie, estradiol and estrone). Androstenedione cytochrome P450 family 19 subfamily A member 1 Homo sapiens