Title : Dissociation of Ca2+ mobilization from breakdown of phosphatidylinositol 4,5-bisphosphate in activated human platelets.

Pub. Date : 1986 Apr

PMID : 3011769






1 Functional Relationships(s)
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1 The early breakdown of phosphatidylinositol 4,5-bisphosphate in human platelets stimulated by a threshold concentration of either collagen or thrombin was inhibited by 5 mM NaF through its inhibition of phospholipase C activity. Phosphatidylinositol 4,5-Diphosphate coagulation factor II, thrombin Homo sapiens